Cisco routers make a fairly basic distinction between the characteristics of a serial line (which you might want to think of as "physical" characteristics) and the characteristics of the protocols running over the line. The physical characteristics of a line are configured by the line command (and various commands that follow it) and include items such as parity and port speed. The high-level protocol characteristics are configured by the interface command (and the commands that follow it); these characteristics include IP addresses and other properties.
The line command can configure:
Getting Started
IOS Images and Configuration Files
Basic Router Configuration
Line Commands
Interface Commands
Networking Technologies
Access Lists
IP Routing Topics
Interior Routing Protocols
Border Gateway Protocol
Quality of Service
Dial-on-Demand Routing
Specialized Networking Topics
Switches and VLANs
Router Security
Troubleshooting and Logging
Quick Reference
Appendix A Network Basics
Index