Editors: Skeel, Roland T.
Title: Handbook of Cancer Chemotherapy, 7th Edition
Copyright 2007 Lippincott Williams & Wilkins
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Editor
Roland T. Skeel MD
Professor of Medicine
College of Medicine, University of Toledo, and Division of Hematology and Oncology, University of Toledo Medical Center, Toledo, Ohio
Secondary Editors
Jonathan W. Pine Jr.
Acquisitions Editor
Anne E. Jacobs
Managing Editor
Alicia Jackson
Project Manager
Benjamin Rivera
Senior Manufacturing Manager
Adam Glazer
Associate Director of Marketing
Holly McLaughlin
Design Coordinator
Becky Baxendell
Cover Designer
Laserwords Private Limited, Chennai, India
Production Service
RR Donnelley-Crawfordsville
Printer
Contributing Authors
Haitham S. Abu-Lebdeh MD
Consultant
Department of Internal Medicine, Mayo Clinic; Assistant Professor, Department of Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota
Stephen Andrews MD
Associate Professor
Department of Gynecologic Oncology, University of Toledo Medical Center; Chief, Division of Gynecologic Oncology, University of Toledo Medical Center, Toledo, Ohio
Rachid Baz MD
Fellow
Department of Special Hematology/ Medical Oncology, Cleveland Clinic Foundation, Cleveland, Ohio
Tracy T. Batchelor MD
Associate Professor
Department of Neurology, Harvard Medical School; Executive Director, Stephen E. and Catherine Pappas Center for Neuro-Oncology; Associate Neurologist, Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts
Robert S. Benjamin MD
Department of Sarcoma Medical Oncology, Division of Cancer Medicine, University of Texas, M.D. Anderson Cancer Center, Houston, Texas
Al B. Benson III MD, FACP
Professor
Department of Medicine, Associate Director for Clinical Investigations, Northwestern University, Feinberg School of Medicine, Robert H. Lurie Comprehensive Cancer Center; Faculty, Department of Medicine, Northwestern Memorial Hospital, Chicago, Illinois
Joseph S. Chan MD
Fellow
Department of Hematology and Medical, Oncology, Oregon Health and Science University, Oregon Health Science, Cancer Institute, Portland, Oregon
Rekha T. Chaudhary MD
Assistant Professor
Department of Medicine, Division of Hematology/Oncology, University of Toledo Medical Center, Toledo, Ohio
Mary E. Cianfrocca MD
Assistant Professor
Department of Medicine, Northwestern University, Feinberg School of Medicine, Chicago, Illinois
Charles S. Cleeland MD, PhD
Chairman
Department of Symptom Research, University of Texas, M.D. Anderson Cancer Center, Houston, Texas
Joan M. Duggan MD
Associate Professor
Department of Internal Medicine, Physiology and Molecular Medicine, University of Toledo; Division of Infectious Diseases, University of Toledo Medical Center, Toledo, Ohio
April F. Eichler MD
Instructor
Department of Neurology, Harvard Medical School; Assistant in Neurology, Department of Neurology, Stephen E. & Catherine Pappas Center for Neuro-Oncology, Massachusetts General Hospital, Boston, Massachusetts
Michael J. Fisch MD, MPH, FACP
Associate Professor
Department of General Oncology; Medical Director, Community Clinical Oncology Program Research Base, University of Texas, M.D. Anderson Cancer Center, Houston, Texas
Kathleen S. N. Franco-Bronson MD
Adjunct Professor
Department of Psychiatry, University of Toledo Medical Center, Toledo, Ohio; Associate Dean of Admissions and Student Affairs, Department of Education and Neuroscience, Cleveland Clinic Lerner College of Medicine/Cleveland Clinic Foundation, Cleveland, Ohio
Olga Frankfurt MD, MS
Instructor
Department of Medicine, Division of Hematology and Oncology, Northwestern University, Feinberg School of Medicine, Robert H. Lurie Comprehensive Cancer Center; Staff Physician, Department of Medicine, Division of Hematology and Oncology, Northwestern Memorial Hospital, Feinberg School of Medicine, Robert H. Lurie Comprehensive Cancer Center, Chicago, Illinois
John P. Greer MD
Professor
Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee
Mohamad A. Hussein MD
Professor of Oncology and Medicine
Department of Interdisciplinary Oncology; Leader Multiple Myeloma Clinical Research, Clinical Director, Department of Interdisciplinary Oncology, Division of Malignant Hematology, University of South Florida College of Medicine & The H. Lee Moffitt Cancer and Research Institute, Tampa, Florida
Chatchada Karanes MD
Director
Cord Blood Transplant Program, Department of Hematology and Hematopoietic Cell Transplant, City of Hope Cancer Center, Duarte, California
Samir N. Khleif MD
Chief
Cancer Vaccine Section, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland
James M. Leonardo MD, PhD
Clinical Associate Professor
Department of Medicine, New York, New York; Associate Director, Bassett Regional Cancer Program, May Imogene Bassett Hospital, Cooperstown, New York
Karen S. Milligan MD
Senior Hematology/Oncology Fellow
Leo Jenkins Cancer Center, East Carolina University, Brody School of Medicine, Greenville, North Carolina
Iman Mohamed MD, FACP, MRCP(UK), MPH
Associate Professor
Department of Medicine, University of Toledo; Division Chief of Hematology & Oncology, Medical Director of the Breast Center, Department of Medicine, University of Toledo Medical Center, Toledo, Ohio
David S. Morgan MD
Associate Professor
Department of Medicine, Vanderbilt University School of Medicine; Division of Hematology and Oncology, Vanderbilt University Medical Center Nashville, Tennessee
Craig R. Nichols MD
Professor
Department of Medicine, Hematology, and Medical Oncology, Oregon Health and Science University, Oregon Health Science Cancer Institute, Portland, Oregon
Harlan A. Pinto MD
Associate Professor
Department of Medicine, Stanford University School of Medicine; Chief of Medical Oncology Section, Veterans Affairs Palo Alto Health Care System, Palo Alto, California
Walter D. Y. Quan Jr. MD
Director of Cancer Immunotherapy
Leo Jenkins Cancer Center; Associate Professor, Department of Medicine, East Carolina University, Brody School of Medicine; Medical Director, 3 West Oncology, Pitt County Memorial Hospital, Greenville, North Carolina
NurJehan Quraishy MD
Clinical Assistant Professor
Department of Pathology, Health Science Campus, University of Toledo; Medical Director, American Red Cross Blood Services, Toledo, Ohio
Roberto Rodriguez MD
Staff Physician
Division of Hematology and Hematopoietic Cell Transplantation, City of Hope Cancer Center, Duarte, California; Staff Physician, Department of Hematology/Oncology, Southern California Permanente Medical Group, Los Angeles, California
Scott B. Saxman MD
Director
Office of Medical Services, Peace Corps, Washington, DC
Joan H. Schiller MD
Professor
Department of Hematology/Oncology, University of Texas, Southwestern Medical School; Chief, Department of Hematology/Oncology, University of Texas Southwestern Medical Center, Dallas, Texas
Roland T. Skeel MD
Professor
Department of Medicine, College of Medicine, University of Toledo and Division of Hematology and Oncology, University of Toledo Medical Center, Toledo, Ohio
Mary R. Smith MD
Professor
Department of Medicine and Pathology, University of Toledo; Division of Hematology and Oncology, University of Toledo Medical Center Toledo, Ohio
Richard S. Stein MD
Professor
Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee
Sophie Sun MD
Assistant Instructor
Department of Hematology/Oncology, University of Texas Southwestern Medical Center, Dallas, Texas
Martin S. Tallman MD
Professor
Department of Medicine, Division of Hematology and Oncology, Northwestern University, Feinberg School of Medicine; Attending Physician, Department of Medicine, Northwestern Memorial Hospital, Chicago, Illinois
Janelle M. Tipton MSN, RN, AOCN
Oncology Clinical Nurse Specialist and Adjunct Instructor of Nursing University of Toledo
University of Toledo Cancer Center, Toledo, Ohio
Mikhail Vinogradov MD
Fellow
Department of Hematology/Oncology, East Carolina University, Brody School of Medicine, Greenville, North Carolina
Paul R. Walker MD, FACP
Clinical Associate Professor
Department of Internal Medicine, Division of Hematology/Oncology, East Carolina University, Brody School of Medicine; Attending in Medical Oncology, Pitt County Memorial Hospital, Greenville, North Carolina
Peter White MD
Emeritus Professor
Department of Medicine, College of Medicine University of Toledo, Toledo, Ohio
Kristi S. Williams MD
Associate Professor
Department of Psychiatry, University of Toledo, Toledo, Ohio