Before saving a file, you can cut down the file size by removing all unnecessary stuff in the file (in this instance, stuff meaning swatches, symbols, patterns, etc.). Thanks to Adobe, it's pretty easy. In the Actions palette (Window>Actions), look in the Default Actions folder for Delete Unused Palette Items. Click on the action name, and press the Play Current Selection button at the bottom of the palette to run the action. All the unused stuff will be removed, so that when you save the document, it will be a little smaller (not all that much in some cases, but every little bit helps, right?).
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