SWISS-PROT is an annotated protein sequence database that was started in 1986. It is currently overseen by the Swiss Institute of Bioinformatics (SIB) in association with the European Bioinformatics Institute (EBI). SWISS-PROT is the preferred protein sequence database for most bioinformaticians because many of the sequence annotations are curated by scientists. TrEMBL, another sequence database, is a computer-annotated supplement that contains all the translations of EMBL nucleotide sequence entries not yet integrated in SWISS-PROT. It has essentially the same sequence flat file format as SWISS-PROT. We're using SWISS-PROT Release 40.