10 - Immobility

Editors: Kane, Robert L.; Ouslander, Joseph G.; Abrass, Itamar B.

Title: Essentials of Clinical Geriatrics, 5th Edition

Copyright 2004 McGraw-Hill

> Table of Contents > Part II - Differential Diagnosis and Management > Chapter 9 - Instability and Falls

Chapter 9

Instability and Falls

Falls are among the major causes of morbidity in the geriatric population. Falling is not only a problem in its own right; it is often a marker for frailty, and falls may be predictors of death as well as indirect causes (usually through fractures). Close to one-third of those aged 65 years and older living at home suffer a fall each year, and about 1 in 40 of those will be hospitalized. Only about half of the elderly patients hospitalized as the result of a fall will be alive a year later. Among geriatric nursing homes residents, as many as half suffer a fall each year; 10 to 25 percent have serious consequences. Accidents are the fifth leading cause of death in persons older than age 65, and falls account for two-thirds of these accidental deaths. Of deaths from falls in the United States, more than 70 percent occur in the 11 percent of the population older than age 65. However, it may be difficult to separate the effects of the accident from the underlying frailty that led to it. Fear of falling can adversely affect older persons' functional status. Repeated falls and consequent injuries can be important factors in the decision to institutionalize an elderly person.

Table 9-1 lists potential complications of falls. Fractures of the hip, femur, humerus, wrist, and ribs, and painful soft-tissue injuries are the most frequent physical complications. Many of these injuries will result in hospitalization, with the attendant risks of immobilization and iatrogenic illnesses (see Chaps. 5 and 10). Fractures of the hip and lower extremities often lead to prolonged disability because of impaired mobility. A less-common, but important, injury is subdural hematoma. Neurological symptoms and signs that develop days to weeks after a fall should prompt consideration of this treatable problem.

TABLE 9-1 COMPLICATIONS OF FALLS IN ELDERLY PATIENTS

Injuries
    Painful soft-tissue injuries
    Fractures
      Hip
      Femur
      Humerus
      Wrist
      Ribs
    Subdural hematoma
Hospitalization
    Complications of immobilization (see Chap. 10)
    Risk of iatrogenic illnesses (see Chap. 5)
Disability
    Impaired mobility because of physical injury
    Impaired mobility from fear, loss of self-confidence, and restriction of ambulation
Risk of institutionalization
Death

Even when the fall does not result in serious injury, substantial disability may result from fear of falling, loss of self-confidence, and restricted ambulation (either self-imposed or imposed by caregivers).

Falls and their attendant complications should be preventable, but it is easier to identify risk factors for falling than to prevent its occurrence. A growing body of studies suggests that at least some types of falls can be prevented. Moreover, it is possible to prevent the untoward consequences of falls (i.e., fractures) by changing the way old people fall. The potential for prevention together with the use of falling as an indicator of underlying frailty combine to make an

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understanding of the causes of falls and a practical approach to the evaluation and management of patients with instability and falls important components of geriatric care. Similar to many other conditions described throughout this text, the factors that can contribute to or cause falls are multiple, and very often more than one of these factors plays an important role (Fig. 9-1).

FIGURE 9-1 Multifactorial causes and potential contributors to falls in older persons.

Falling may be a useful indicator of frailty in general. Persons with a history of falling have higher levels of subsequent health care use and poor functional status. Fallers who were thoroughly assessed showed a benefit in functional outcomes over those who were not, even when the cause of the fall could not be determined or treated.

AGING AND INSTABILITY

Several age-related factors contribute to instability and falls (Table 9-2). Most accidental falls are caused by one or a combination of these factors interacting with environmental hazards.

TABLE 9-2 AGE-RELATED FACTORS CONTRIBUTING TO INSTABILITY AND FALLS

Changes in postural control
     Decreased proprioception
     Slower righting reflexes
     Decreased muscle tone
     Increased postural sway
     Orthostatic hypotension
Changes in gait
     Feet not picked up as high
     Men: develop flexed posture and wide-based, short-stepped gait
     Women: develop narrow-based, waddling gait
Increased prevalence of pathologic conditions relative to stability
     Degenerative joint disease
     Fractures of hip and femur
     Stroke with residual deficits
     Muscle weakness from disuse and deconditioning
     Peripheral neuropathy
     Diseases or deformities of the feet
     Impaired vision
     Impaired hearing
     Forgetfulness and dementia
     Other specific disease processes (e.g., cardiovascular disease, parkinsonism see Table 9-3)
Increased prevalence of conditions causing nocturia (e.g., congestive heart failure, venous insufficiency)
Increased prevalence of dementia

Aging changes in postural control and gait probably play a major role in many falls among older persons. Increasing age is associated with diminished proprioceptive

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input, slower righting reflexes, diminished strength of muscles important in maintaining posture, and increased postural sway. All these changes can contribute to falling especially the ability to avoid a fall after encountering an environmental hazard or an unexpected trip. Changes in gait also occur with increasing age. Although these changes may not be sufficiently prominent to be labeled truly pathological, they can increase susceptibility to falls. In general, elderly people do not pick their feet up as high, thus increasing the tendency to trip. Elderly men develop wide-based, short-stepped gaits; elderly women often walk with a narrow-based, waddling gait. Orthostatic hypotension (defined as a drop in systolic blood pressure of 20 mm Hg or more when moving from a lying to a standing position) occurs in approximately 20 percent of older persons. Although not all elderly individuals with orthostatic hypotension are symptomatic, this impaired physiological response could play a role in causing instability and precipitating falls in a substantial proportion of patients. Older people have been shown to experience a postprandial fall in blood pressure as well.

Several pathological conditions that increase in prevalence with increasing age can contribute to instability and falling. Degenerative joint disease (especially of the neck, the lumbosacral spine, and the lower extremities) can cause pain, unstable joints, muscle weakness, and neurological disturbances. Healed fractures of the hip and femur can cause an abnormal and less steady gait. Residual muscle weakness or sensory deficits from a recent or remote stroke can cause instability.

Muscle weakness as a result of disuse and deconditioning (caused by pain and/or lack of exercise) can contribute to an unsteady gait and impair the ability

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to right oneself after a loss of balance. Diminished sensory input, such as in diabetic and other peripheral neuropathies, visual disturbances, and impaired hearing diminish cues from the environment that normally contribute to stability and thus predispose one to falls. Impaired cognitive function may result in the creation of, or wandering into, unsafe environments and may lead to falls. Podiatric problems (bunions, calluses, nail disease, joint deformities, etc.) that cause pain, deformities, and alterations in gait are common, correctable causes of instability. Other specific disease processes common in older people (such as Parkinson's disease and cardiovascular disorders) can cause instability and falls and are discussed further below.

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Inability to get up after a fall can be an indication of a poor prognosis. In one study almost half those who fell at least once reported being unable to get up. These older persons had poorer functional outcomes.

CAUSES OF FALLS IN OLDER PERSONS

Table 9-3 outlines the multiple and often interacting causes of falls among older persons. More than half of all falls are related to medically diagnosed conditions, emphasizing the importance of a careful medical assessment for patients who fall (see below). Several studies have examined risk factors for falls among older persons and have found a variety of these factors including cognitive impairment, disabilities of the lower extremities, gait and balance abnormalities, nocturia, and the number and nature of medications being taken as important risk factors. Frequently overlooked, environmental factors can increase susceptibility to falls and other accidents. Homes of elderly people are often full of environmental hazards (Table 9-4). Unstable furniture, rickety stairs with inadequate railings, throw rugs and frayed carpets, and poor lighting should be specifically looked for on home visits. Several factors are associated with falls among older nursing home residents (Table 9-5). Awareness of these factors can help prevent morbidity and mortality in these settings. Although attention to the environment makes sense, the role of environmental hazards may be overemphasized (Gill et al., 2000).

TABLE 9-3 CAUSES OF FALLS

Accidents
     True accidents (trips, slips, etc.)
     Interactions between environmental hazards and factors increasing susceptibility (see Table 9-2)
Syncope (sudden loss of consciousness)
Drop attacks (sudden leg weaknesses without loss of consciousness)
Dizziness and/or vertigo
     Vestibular disease
     Central nervous system disease
Orthostatic hypotension
     Hypovolemia or low cardiac output
     Autonomic dysfunction
     Impaired venous return
     Prolonged bed rest
     Drug-induced hypotension
     Postprandial hypotension
Drug-related causes
     Diuretics
     Antihypertensives
     Tricyclic antidepressants
     Sedatives
     Antipsychotics
     Hypoglycemics
     Alcohol
Specific disease processes
     Acute illness of any kind ( premonitory fall )
     Cardiovascular
       Arrhythmias
       Valvular heart disease (aortic stenosis)
       Carotid sinus syncope
     Neurological causes
       Transient ischemic attack (TIA)
       Stroke (acute)
       Seizure disorder
       Parkinson's disease
       Cervical or lumbar spondylosis (with spinal cord or nerve root compression)
       Cerebellar disease
       Normal-pressure hydrocephalus (gait disorder)
       Central nervous system lesions (e.g., tumor, subdural hematoma)
Idiopathic (no specific cause identifiable)

TABLE 9-4 COMMON ENVIRONMENTAL HAZARDS

Old, unstable, and low-lying furniture
Beds and toilets of inappropriate height
Unavailability of grab bars
Uneven stairs and inadequate railing
Throw rugs, frayed carpets, cords, wires
Slippery floors and bathtubs
Inadequate lighting, glare
Cracked and uneven sidewalks

TABLE 9-5 FACTORS ASSOCIATED WITH FALLS AMONG OLDER NURSING HOME RESIDENTS

Recent admission
Dementia
Hip weakness
Certain activities (toileting, getting out of bed)
Psychotropic drugs causing daytime sedation
Cardiovascular medications (vasodilators, diuretics)
Polypharmacy
Low staff patient ratio
Unsupervised activities
Unsafe furniture
Slippery floors

Several factors can hinder precise identification of the specific causes for falls. These factors include lack of witnesses, inability of the elderly person to recall the circumstances surrounding the event, the transient nature of several causes [e.g., arrhythmia, transient ischemic attack (TIA), postural hypotension], and the fact that the majority of elderly people who fall do not seek medical attention. Somewhat more detailed information is available on the circumstances surrounding falls in nursing homes (see Table 9-5), but these individuals represent a relatively low proportion and a highly select group among the total senior population.

Close to half of all falls can be classified as accidental. Usually an accidental trip or a slip can be precipitated by an environmental hazard, often in conjunction with factors listed in Table 9-2. Addressing the environmental hazards begins with a careful assessment of the patient's environment. Some older persons have developed a strong attachment to their cluttered surroundings and may need active encouragement to make the necessary changes, but many may simply take such environmental risks for granted until they are specifically identified.

Syncope, drop attacks, and dizziness are commonly cited causes of falls in elderly persons. Indeed, dizziness has been nominated as a possible geriatric syndrome, worthy of fuller exploration (Tinetti et al., 2000). If there is a clear history of loss of consciousness, a cause for true syncope should be sought. Although the complete differential diagnosis of syncope is beyond the scope of

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this chapter, some of the more common causes of syncope in older people include vasovagal responses, cardiovascular disorders (such as brady- and tachyarrhythmias and aortic stenosis), acute neurological events (such as TIA, stroke, and seizure), pulmonary embolus, and metabolic disturbances (e.g., hypoxia, hypoglycemia). Cardiovascular causes for syncope are more common in the elderly than in younger populations. A precise cause for syncope may remain unidentified in 40 to 60 percent of elderly patients.

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Drop attacks, described as sudden leg weakness causing a fall without loss of consciousness, are probably overdiagnosed in elderly people who fall. They are often attributed to vertebrobasilar insufficiency, frequently precipitated by a change in head position. Only a small proportion of older people who fall have truly had a drop attack. The underlying pathophysiology is poorly understood, and care should be taken to rule out other causes.

Dizziness and unsteadiness are extremely common complaints among elderly people who fall (as well as those who do not). A feeling of light-headedness can be associated with several different disorders, but is a nonspecific symptom and should be interpreted with caution. Patients complaining of light-headedness should be carefully evaluated for postural hypotension and intravascular volume depletion.

Vertigo (a sensation of rotational movement), on the other hand, is a more specific symptom and is probably an uncommon precipitant of falls in the elderly. It is most commonly associated with disorders of the inner ear, such as acute labyrinthitis, M ni re's disease, and benign positional vertigo. Vertebrobasilar ischemia and infarction and cerebellar infarction can also cause vertigo. Patients with vertigo caused by organic disorders often have nystagmus, which can be observed by having the patient quickly lie down and turning the patient's head to the side in one motion. Many older patients with symptoms of dizziness and unsteadiness are anxious, depressed, and chronically afraid of falling, and the evaluation of their symptoms is quite difficult. Some patients, especially those with symptoms suggestive of vertigo, will benefit from a thorough otological examination including auditory testing, which may help clarify the symptoms and differentiate inner-ear from central nervous system (CNS) involvement.

Orthostatic hypotension is best detected by taking the blood pressure and pulse in supine position, after 1 minute in the sitting position, and after 1 and 3 minutes in the standing position. A drop of more than 20 mm Hg in systolic blood pressure is generally considered to represent significant orthostatic hypotension. In many instances, this condition is asymptomatic; however, several conditions can cause orthostatic hypotension or worsen it to a severity sufficient to precipitate a fall.

These conditions include low cardiac output from heart failure or hypovolemia, autonomic dysfunction (which can result from diabetes or Parkinson's disease), impaired venous return (e.g., venous insufficiency), prolonged bed rest with deconditioning of muscles and reflexes, and several different drugs. Simply eating a full meal can precipitate a reduction in blood pressure in an older person that may be worsened and precipitate a fall when the person stands up. The association of orthostatic hypotension with elevated blood pressure but not with the use of antihypertensive medication suggests that treatment of hypertension may improve this condition.

Drugs that should be suspected of playing a role in falls include diuretics (hypovolemia), antihypertensives (hypotension), tricyclic antidepressants (postural

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hypotension), sedatives (excessive sedation), antipsychotics (sedation, muscle rigidity, postural hypotension), hypoglycemics (acute hypoglycemia), and alcohol (intoxication). Combinations of these drug types may greatly increase the risk of a fall. Psychotropic drugs are commonly prescribed and appear to substantially increase the risk of falls and hip fractures, especially in patients prescribed tricyclic antidepressants.

Many disease processes, especially of the cardiovascular and neurological systems, can be associated with falls. Cardiac arrhythmias are common in ambulatory elderly persons and may be difficult to associate directly with a fall or syncope. In general, cardiac monitoring should document a temporal association between a specific arrhythmia and symptoms (or a fall) before the arrhythmia is diagnosed (and treated) as the cause of falls.

Syncope can be a symptom of aortic stenosis and is an indication of the need to evaluate a patient suspected of having significant aortic stenosis for valve replacement. Aortic stenosis is difficult to diagnose by physical examination alone, and all patients suspected of having this condition should have an echocardiogram.

Some elderly individuals have sensitive carotid baroreceptors and are susceptible to syncope resulting from reflex increase in vagal tone (caused by cough, straining at stool, micturition, etc.), which leads to bradycardia and hypotension. Carotid sinus sensitivity can be detected by bedside maneuvers (see below).

Cerebrovascular disease is often implicated as a cause or contributing factor for falls in older patients. Although cerebral blood flow and cerebrovascular autoregulation may be diminished, these aging changes alone are not enough to cause unsteadiness or falls. They may, however, render the elderly person more susceptible to stresses such as diminished cardiac output, which will more easily precipitate symptoms. Acute strokes (caused by thrombosis, hemorrhage, or embolus) can cause and may initially manifest themselves in falls. TIAs of both the anterior and posterior circulations frequently last only minutes and are often poorly described. Thus, care must be taken in making these diagnoses. Anterior circulation TIAs may cause unilateral weakness and thus precipitate a fall. Vertebrobasilar (posterior circulation) TIAs may cause vertigo, but a history of transient vertigo alone is not a sufficient basis for the diagnosis of a TIA. The diagnosis of posterior circulation TIA necessitates that one or more other symptoms (visual field cuts, dysarthria, ataxia, or limb weakness which can be bilateral) be associated with vertigo. Vertebrobasilar insufficiency, as mentioned above, is often cited as a cause of drop attacks; in addition, mechanical compression of the vertebral arteries by osteophytes of the cervical spine when the head is turned has also been proposed as a cause of unsteadiness and falling. Both of these conditions are poorly documented, are probably overdiagnosed, and should not be used as causes of a fall simply because nothing else can be found.

Other diseases of the brain and central nervous system can also cause falls. Parkinson's disease and normal-pressure hydrocephalus can cause disturbances of gait, which lead to instability and falls. Cerebellar disorders, intracranial

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tumors, and subdural hematomas can cause unsteadiness, with a tendency to fall. A slowly progressive gait disability with a tendency to fall, especially in the presence of spasticity or hyperactive reflexes in the lower extremities, should prompt consideration of cervical spondylosis and spinal cord compression. It is especially important to consider these diagnoses because treatment may improve the condition before permanent disability ensues.

Despite this long list, the precise causes of many falls will remain unknown even after a thorough evaluation. The ultimate test of the etiology for falls is its reversibility. As noted earlier, we are better at finding putative causes than in correcting them.

EVIDENCE ON FALLS PREVENTION

The intense effort to identify risk factors for falls has been matched more recently with interventive efforts. A recent meta-analysis concluded that there was evidence that interventions could prevent the rate of falls, but the cost-effectiveness of falls prevention still remains unclear (RAND, 2002). Table 9-6 summarizes some of the findings from these studies. In general, they suggest that it is possible to reduce the rate of falling, but not the rate of injurious falls. Despite this mixed message, there is growing enthusiasm for undertaking preventive efforts. Moreover, good clinical sense still dictates active efforts to identify remediable risk factors. A randomized trial showed that targeted intervention to reduce the rate of falls did lower the overall rate (as compared with a control group) but there was no significant difference in the rate of serious falls. A meta-analysis of the several studies conducted under the auspices of the Frailty and Injuries: Cooperative Studies of Intervention Techniques (FICSIT) trials showed only modest results. In only two cases did an intervention lead to a significant reduction in falls; exercise and balance were associated with fewer falls, but not with falls with injuries. Tai Chi training was shown to increase the time to a fall but not to a serious fall compared with an educational control group. When a specific fall prevention program was compared with a more general chronic disease prevention program, the falls program achieved lower rates of falls and serious falls at the end of the first year, but by year 2, the differences disappeared. A New Zealand study showed that elderly patients could be taught at home to perform exercises that reduced the rate of falls. A fact to remember when interpreting the effect of exercise in falls prevention is that exercise needs to be sustained, probably for at least 6 months. The dropout rate for many of these exercise programs is quite high (approximately one-third to one-half of participants), suggesting that at least part of the problem in demonstrating an effect may lie in maintaining the intervention.

TABLE 9-6 SUMMARY OF FALLS INTERVENTION STUDIES

INTERVENTION FINDINGS REFERENCE
Exercise and cognitive-behavioral therapy No difference in time to first fall Reinsch et al., 1992
Combination of medication adjustment, behavioral instructions, exercise program At 1 year RR for falls 0.69; no significant effect on injurious falls Tinetti et al., 1994
Removing safety hazards, behavior program, strength, range of motion, and proprioception exercises At 2 years RR for falling 0.85; no significant effect on injurious falls Hornbrook et al., 1994
Nurse home assessment with and without specific attention to falls risks Both intervention groups have lower rates of falls and injurious falls after 1 year, but not at 2 years Wagner et al., 1994
Various exercise programs RR for falls among general exercise group 0.90, including balance 0.83; no significant effect on injurious falls FICSIT (Province et al., 1995)
Tai Chi Relative hazard for falling 0.51 Wolf et al., 1996
Strength and endurance training Relative hazard for falls 0.53 Buchner et al., 1997
Weight-bearing exercise Number of falls over 2 years not significant but difference in rate for months 12 18 was significant McMurdo et al., 1997
Home-based physical therapy exercise program Hazard ratio for first fall was not significant, but for fall with injury it was 0.61 Campbell et al., 1997
Medical and occupational therapy assessment and referrals RR for falls at 12 mo 0.39, for recurrent falls 0.33; RR for hospital admission 0.61 PROFET (Close et al., 1999)
Home-based strength and balance exercise program RR for falls at 2 years 0.69; RR for moderate/severe injury 0.63 Campbell et al., 1999
Home visit by occupational therapist for environmental assessment and modification Decrease in number of persons falling; among prior fallers, RR of fall was 0.64 Cumming et al., 1999
Falls prevention strategies in nursing homes Only two-thirds completed 6-mo intervention; no difference in fall rates McMurdo et al., 2000
Additive model: education, exercise, home safety advice, clinical assessment Compared to education group, significant reduction in slips and trips, but not falls Steinberg et al., 2000
Home hazard assessment, information on hazard reduction, installation of safety devices No significant difference in rate of falls in the home Stevens et al., 2001
Nurse-delivered home exercise program Significant decrease in numbers of falls and serious injurious falls Robertson et al., 2001
Multiple strategies in residential care facilities (education, environmental modifications, reviewing drug regimens, etc.) Adjusted OR for falls 0.49; adjusted incidence rate for falls 0.60 Jensen et al., 2002
Abbreviations: OR = odds ratio; RR = relative risk.

A successful multifactorial approach to reducing falls among nursing home patients employed training in environmental and personal safety, wheelchair use,

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psychotropic drug management, and transferring and ambulation. Although not immediately connected to reducing fall risks, a study directed at frail nursing home patients showed that moderate exercise improved gait and stair-climbing ability. A multifactorial intervention study among residential care facility residents, which combined staff education with environmental modifications, attention to drug regimens, and exercise programs, reduced the rate of falls

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significantly. If the falls per se cannot be prevented, the risk of fractures can be reduced by having those at high risk wear external hip protectors (Kannus et al., 2000; Parker, 2001).

Studies of instructional environments suggest that carpeted floors are associated with fewer falls than vinyl floors (Healey, 1994). Likewise, the use of bed alarms is associated with a reduction in the fall rate among hospitalized patients (Tideiksaar et al., 1993). Although many people think of physical restraints as a means of preventing falls, the evidence points in the opposite direction.

EVALUATING THE ELDERLY PATIENT WHO FALLS

Older patients who report a fall (or recurrent falls) that is not clearly the result of an accidental trip or slip should be carefully evaluated, even if the falls have not resulted in serious physical injury. A jointly developed set of recommendations for assessing people who fall has been issued by the American Geriatrics Society, The British Geriatrics Society, and the American Academy of Orthopaedic Surgeons (American Geriatrics Society et al., 2001). Table 9-7 lists the hallmarks of these recommendations. An example of an assessment from for older patients who fall is included in the Appendix. A thorough fall evaluation consists of a detailed history, physical examination, gait and balance assessment, and, in certain instances, selected laboratory studies.

TABLE 9-7 RECOMMENDATIONS FOR FALLS ASSESSMENT

  1. All older people should be asked about falls in the prior year.
  2. Those with a single prior fall should have a get-up-and-go test or its equivalent (rising from a chair without using their arms and walking at a reasonable rate). Those who pass and have no history of falling need nothing further.
  3. Those with two or more falls should be given a full falls assessment.
  4. Fall assessment consists of:
    • History of fall circumstances, medications, acute or chronic medical problems, and mobility levels
    • Examination of vision, gait and balance, and lower extremity joint function
    • Basic neurological examination (mental status, muscle strength, lower extremity peripheral nerves, proprioception, reflexes, tests of cortical, extrapyramidal, and cerebellar function
    • Basic cardiovascular assessment (heart rate and rhythm, postural pulse and blood pressure, and possibly carotid sinus stimulation test)
Source: American Geriatrics Society, et al., 2001.

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The history should focus on the general medical history and medications, the patient's thoughts about what caused the fall, the circumstances surrounding it, any premonitory or associated symptoms (such as palpitations caused by a transient arrhythmia or focal neurological symptoms caused by a TIA), and whether there was loss of consciousness (Table 9-8). A history of loss of consciousness after the fall (which is often difficult to document) is important information and should raise the suspicion of a cardiac event (transient arrhythmia or heart block) or a seizure (especially if there has been incontinence). Falls are often unwitnessed, and elderly patients may not recall any details of the circumstances surrounding the event. Detailed questioning can sometimes lead to identification of environmental factors that may have played a role in the fall and to symptoms that may lead to a specific diagnosis. Many elderly patients will not be able to give details about an unwitnessed fall and will simply report, I just fell down, I don't

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know what happened. The skin, extremities, and painful soft-tissue areas should be assessed to detect any injury that may have resulted from a fall.

TABLE 9-8 EVALUATING THE ELDERLY PATIENT WHO FALLS: KEY POINTS IN THE HISTORY

General medical history
History of previous falls
Medications (especially antihypertensive and psychotropic agents)
Patient's thoughts on the cause of the fall
    Was patient aware of impending fall?
    Was it totally unexpected?
    Did patient trip or slip?
Circumstances surrounding the fall
    Location and time of day
    Witnesses
    Relationship to changes in posture, turning of head, cough, urination
Premonitory or associated symptoms
    Light-headedness, dizziness, vertigo
    Palpitations, chest pain, shortness of breath
    Sudden focal neurologic symptoms (weakness, sensory disturbance, dysarthria, ataxia, confusion, asphasia)
    Aura
    Incontinence of urine or stool
Loss of consciousness
    What is remembered immediately after the fall?
    Could the patient get up and, if so, how long did it take?
    Can loss of consciousness be verified by a witness?

Several other aspects of the physical examination can be helpful in determining the cause(s) (Table 9-9). Because a fall can herald the onset of a variety of acute illnesses ( premonitory falls), careful attention should be given to vital signs. Fever, tachypnea, tachycardia, and hypotension should prompt a search for an acute illness (such as pneumonia or sepsis, myocardial infarction, pulmonary embolus, or gastrointestinal bleeding). Postural blood pressure and pulse determinations taken supine, sitting, and standing (after 1 and 3 minutes) are critical in the diagnosis and management of falls in older patients. As noted earlier, postural hypotension occurs in a substantial number of healthy, asymptomatic elderly persons as well as in those who are deconditioned from immobility or have venous insufficiency. This finding can also be a sign of dehydration, acute blood loss (occult gastrointestinal bleeding), or a drug side effect. Visual acuity should be assessed for any possible contribution to instability and falls. The cardiovascular examination should focus on the presence of arrhythmias (many of which are easily missed during a brief examination) and signs of aortic stenosis. Because both of these conditions are potentially serious and treatable, yet difficult to diagnose by physical examination, the patient should be referred for continuous monitoring and echocardiography if they are suspected. If the history suggests carotid sinus sensitivity, the carotid can be gently massaged for 5 seconds to observe whether this precipitates a profound bradycardia (50 percent reduction in heart rate) or a long pause (2 seconds). The extremities should be examined for evidence of deformities, limits to range of motion, or active inflammation that might underlie instability and cause a fall.

TABLE 9-9 EVALUATING THE ELDERLY PATIENT WHO FALLS: KEY ASPECTS OF THE PHYSICAL EXAMINATION

Vital signs
     Fever, hypothermia
     Respiratory rate
     Pulse and blood pressure (lying, sitting, standing)
Skin
     Turgor
     Pallor
     Trauma
Eyes
     Visual acuity
Cardiovascular
     Arrhythmias
     Carotid bruits
     Signs of aortic stenosis
     Carotid sinus sensitivity
Extremities
     Degenerative joint disease
     Range of motion
     Deformities
     Fractures
     Podiatric problems (calluses; bunions; ulcerations; poorly fitted, inappropriate, or worn-out shoes)
Neurological
     Mental status
     Focal signs
     Muscles (weakness, rigidity, spasticity)
     Peripheral innervation (especially position sense)
     Cerebellar (especially heel-to-shin testing)
     Resting tremor, bradykinesia, other involuntary movements
     Observing the patient stand up and walk (the get-up-and-go test)

Special attention should be given to the feet because deformities, painful lesions (calluses, bunions, ulcers), and poorly fitted, inappropriate, or worn-out shoes are common and can contribute to instability and falls.

Neurological examination is also an important aspect of this physical assessment. Mental status should be assessed (see Chap. 6), with a careful search for focal neurological signs. Evidence of muscle weakness, rigidity, or spasticity should be noted, and signs of peripheral neuropathy (especially posterior column signs such as loss of position or vibratory sensation) should be ruled out. Abnormalities in cerebellar function (especially heel-to-shin testing) and signs of Parkinson's disease (such as resting tremor, muscle rigidity, and bradykinesia) should be sought.

Gait and balance assessments are a critical component of the examination and are probably more useful in identifying remediable problems than is the standard neuromuscular exam. Although sophisticated techniques have been developed to assess gait and balance, careful observation of a series of maneuvers is the most practical and useful assessment technique. The get-up-and-go test and other practical performance-based balance and gait assessments have been developed. Tables 9-10 and 9-11 provide examples of these types of assessment. Abnormalities on these assessments may be helpful in identifying patients who

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are likely to fall again and potentially remediable problems that might prevent future falls.

TABLE 9-10 EXAMPLE OF A PERFORMANCE- BASED ASSESSMENT OF GAIT

COMPONENTS OBSERVATION
NORMAL ABNORMAL
Initiation of gait (patient asked to begin walking down hallway at a normal pace using any assistive device they normally walk with) Begins walking immediately without observable hesitation; initiation of gait is single, smooth motion Hesitates; multiple attempts; initiation of gait not a smooth motion
Step height (begin observing after first few steps: observe one foot, then the other; observe from side) Swing foot completely clears floor but by no more than 1 2 in. Swing foot is not completely raised off floor (may hear scraping) or is raised too high (1 <2 in.)
Step length (observe distance between toe of stance foot and heel of swing foot; observe from side; do not judge first few or last few steps; observe one side at a time) At least the length of individual's foot between the stance toe and swing heel (step length usually longer but foot length provides basis for observation) Step length less than described under normal
Step symmetry (observe the middle part of the path, not the first or last steps; observe from side; observe distance between heel of each swing foot and toe of each stance foot) Step length same or nearly same on both sides for most step cycles Step length varies between sides, or patient advances with same foot every step
Step continuity Begins raising heel of one foot (toe off) as heel of other foot touches the floor (heel strike); no breaks or stops in stride; step lengths equal over most cycles Places entire foot (heel and toe) on floor before beginning to raise other foot; or stops completely between steps; or step length varies over cycles
Path deviation [observe from behind; observe one foot over several strides; observe in relation to line on floor (e. g., tiles) if possible; difficult to assess if patient uses a walker] Foot follows close to straight line as patient advances Foot deviates from side to side or toward one direction
Trunk stability (observe from behind; side-to-side motion of trunk may be a normal gait pattern; need to differentiate this from instability) Trunk does not sway; knees or back are not flexed; arms are not abducted in effort to maintain stability Any of preceding features present
Walk stance (observe from behind) Feet should almost touch as one passes other Feet apart with stepping
Turning while walking No staggering; turning continuous with walking; steps are continuous while walking; steps are continuous while turning Staggers; stops before initiating turn; or steps are discontinuous
Source: From Tinetti, 1986, with permission.

TABLE 9-11 EXAMPLE OF A PERFORMANCE BASED-ASSESSMENT OF BALANCE

MANEUVER NORMAL ADAPTIVE ABNORMAL
Sitting balance Steady, stable Holds onto chair to keep upright Leans, slides down in chair
Arising from chair Able to arise in a single movement without using arms Uses arms (on chair or walking aid) to pull or push up and/ or moves forward in chair before attempting to rise Multiple attempts required or unable without human assistance
Immediate standing balance (first 3 5 s) Steady without holding onto walking aid or other object for support Steady, but uses walking aid or support grabbing objects for support Any sign of unsteadiness (e.g., other object for staggering, more than minimal trunk sway)
Standing balance Steady, able to stand with feet together without holding onto an object for support Steady, but cannot put feet together  
Balance with eyes closed (with feet as close together as possible) Steady without holding onto any object with feet together Steady with feet apart Any sign of unsteadiness or needs to hold onto an object
Turning balance (360 ) No grabbing or staggering; no need to hold onto any objects; steps are continuous (turn is a flowing movement) Steps are discontinuous (patient puts one foot completely on floor before raising other foot) Any sign of unsteadiness or holds onto an object
Nudge on sternum (patient standing with feet as close together as possible; examiner pushes with light, even pressure over sternum three times; reflects ability to withstand displacement) Steady, able to withstand pressure Needs to move feet, but able to maintain balance Begins to fall, or examiner has to help maintain balance
Neck turning (patient asked to turn head side to side and look up while standing with feet as close together as possible) Able to turn head at least halfway side to side and able to bend head back to look at ceiling; no staggering, grabbing, or symptoms of light-headedness, unsteadiness, or pain Decreased ability to turn side to side to extend neck, but no staggering, grabbing, or symptoms of light-headedness, unsteadiness, or pain Any sign of unsteadiness or symptoms when turning head or extending neck
One-leg standing balance Able to stand on one leg for 5 s without holding onto object for support Unable
Back extension (ask patient to lean back as far as possible, without holding onto object if possible) Good extension without holding object or staggering Tries to extend, but range of motion is decreased or needs to hold object to attempt extension Will not attempt, no extension seen, or staggers
Reaching up (have patient attempt to remove an object from a shelf high enough to necessitate stretching or standing on toes) Able to take down object without needing to hold onto other object for support and without becoming unsteady Able to get object but needs to steady self by holding onto something for support Unable or unsteady
Bending down (patient is asked to pick up small objects, such as pen, from the floor) Able to bend down and pick up the object and able to get up easily in single attempt without needing to pull self up with arms Able to get object and get upright in single attempt but needs to pull self up with arms or hold onto something for support Unable to bend down or unable to get upright after bending down or takes multiple attempts to upright self
Sitting down Able to sit down in one smooth movement Needs to use arms to guide self into chair or not a smooth movement Falls into chair, misjudges distances (lands off center)

There is no specific laboratory workup for an elderly patient who falls. Laboratory studies should be ordered based on information gleaned from the history and physical examination. If the cause of the fall is obvious (such as a slip or a trip) and no suspicious symptoms or signs are detected, laboratory studies are unwarranted. If the history or physical examination (especially vital signs) suggests an acute illness, appropriate laboratory studies (such as complete blood count, electrolytes, blood urea nitrogen, chest films, electrocardiogram) should be ordered. If a transient arrhythmia or heart block is suspected, ambulatory electrocardiographic monitoring should be done. Although the sensitivity and specificity of this procedure for determining the cause of falls in the elderly is unknown, and many elderly people have asymptomatic ectopy, cardiac abnormalities detected on continuous monitoring that are clearly related to symptoms should be treated.

Because it is difficult to diagnose aortic stenosis on physical examination, echocardiography should be considered in all patients with suggestive histories and a systolic heart murmur or those who have a delay in the carotid upstroke. If the history suggests anterior circulation TIA, noninvasive vascular studies should be considered to rule out treatable vascular lesions. Computed tomography (CT) scans and electroencephalograms should be reserved for those patients in whom there is a high suspicion of an intracranial lesion or seizure disorder.

MANAGEMENT

Table 9-12 outlines the basic principles of managing elderly patients with instability problems and a history of falls. Assessment and treatment of physical injury should not be overlooked because it may be helpful in preventing recurrent falls.

TABLE 9-12 PRINCIPLES OF MANAGEMENT FOR ELDERLY PATIENTS WITH COMPLAINTS OF INSTABILITY AND/OR FALLS

Assess and treat physical injury
Treat underlying conditions (Table 9-13)
Provide physical therapy and education
     Gait retraining
     Muscle strengthening
     Aids to ambulation
     Properly fitted shoes
     Adaptive behaviors
Alter the environment
     Safe and proper-size furniture
     Elimination of obstacles (loose rugs, etc.)
     Proper lighting
     Rails (stairs, bathroom)

When specific conditions are identified by history, physical examination, and laboratory studies, they should be treated in order to minimize the risk of subsequent falls, morbidity, and mortality. Table 9-13 lists examples of treatments for some of the more common conditions. This table is meant only as a general outline; most of these topics are discussed in detail in general textbooks of medicine.

TABLE 9-13 EXAMPLES OF TREATMENT FOR UNDERLYING CAUSES OF FALLS

CONDITION AND CAUSE POTENTIAL TREATMENT
CARDIOVASCULAR
Tachyarrhythmias Antiarrhythmics*
Bradyarrhythmias Pacemaker*
Aortic stenosis Valve surgery (for syncope)
Postural hypotension
     Drug-related Elimination of drugs(s)
     With venous insufficiency Support stockings
Leg elevation
Adaptive behaviors
Autonomic dysfunction or idiopathic Support stockings
Mineralocorticoids
ProAmatine (Midodrine hydrochloride)
Adaptive behaviors
NEUROLOGICAL
Anterior circulation transient ischemic attack (TIA) Aspirin and/or surgery
Posterior circulation TIA Aspirin
Cervical spondylosis (with spinal cord compression) Physical therapy
Neck brace
Surgery
Parkinson's disease Antiparkinsonian drugs
Visual impairment Ophthalmological evaluation and specific treatment
Seizure disorder Anticonvulsants
Normal-pressure hydrocephalus Surgery (shunt)
Dementia Supervised activities
Hazard-free environment
Benign positional vertigo Habituation exercises
Antivertiginous medication
OTHERS
Foot disorders Podiatric evaluation and treatment
Gait disorders (miscellaneous) Properly fitted shoes
Physical therapy
Drug overuse (e.g., sedatives, alcohol, other psychotropic drugs, antihypertensives) Elimination of drug(s)
* These treatments may be indicated only if the cardiac disturbance is clearly related to symptoms.
Risk:benefit ratio must be carefully assessed.

Physical therapy and patient education are important aspects of the management of these elderly patients. Gait training, muscle strengthening, the use of assistive devices, and adaptive behaviors (such as rising slowly, using rails or furniture for balance, and techniques of getting up after a fall) are all helpful in preventing subsequent morbidity from instability and falls.

Environmental manipulations can be critical in preventing further falls. The environments of the elderly are often unsafe (see Table 9-4), and appropriate interventions can often be instituted to improve safety (see Table 9-13). Physical restraints (vests, belts, mittens, geri-chairs, etc.) are commonly used in institutional settings for those felt to be at high risk of falling. Nursing home regulations

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in the Omnibus Budget Reconciliation Act of 1987, and the increasing recognition that physical restraints probably do not decrease and may in fact increase falls and injuries (Tinetti et al., 1992; Neufeld et al., 1999), have led to the reduced and more appropriate use of these devices in many institutional settings.

The same multiorganization group noted earlier has also offered a series of recommendations on interventions. Table 9-14 summarizes these recommendations. Here, too, the scientific strength of the recommendations is limited.

TABLE 9-14 RECOMMENDED FALL INTERVENTIONS TO PREVENT FALLS

  1. Among community-dwelling older persons
    • Gait training and advice on appropriate assistive devices
    • Review and modify medication, especially psychotropics
    • Exercise programs that include balance
    • Treat postural hypertension
    • Modify environmental hazards
    • Treat cardiovascular disorders, including arrhythmias
  2. In long-term care and assisted-living settings
    • Staff education programs
    • Gait training and advice on appropriate assistive devices
    • Review and modify medication, especially psychotropics
Source: American Geriatrics Society et al., 2001

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Suggested Readings

Agostini JV, Baker DI, Bogardus STJ: Prevention of falls in hospitalized and institutionalized older people: Making Health Care Safer: A Critical Analysis of Patient Safety Practices. Rockville, MD, Agency for Healthcare Research and Quality, 2001.

Alexander N: Gait disorders in older adults. J Am Geriatr Soc 44:434 451, 1996.

Connell B: Role of the environment in falls prevention. Clin Geriatr Med 12:859 880, 1996.

Gillespie LD, Gillespie WJ, Robertson MC, et al: Interventions for preventing falls in elderly people. Cochrane Database of Syst Rev 3:CD000340, 2001.

King MB, Tinetti ME: Falls in community-dwelling older persons. J Am Geriatr Soc 43:1146 1154, 1995.

Luukinen H, Koski K, Konkanen R: Incidence of injury-causing falls among older adults by place of residence: a population-based study. J Am Geriatr Soc 43:871 876, 1995.

Tinetti ME: Preventing falls in elderly persons. N Engl J Med 348:42 49, 2003.



Essentials of Clinical Geriatrics
Understanding Thin Client/Server Computing (Strategic Technology Series)
ISBN: 71498222
EAN: 2147483647
Year: 2002
Pages: 23
Authors: Joel P Kanter

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