Chapter 4. Pfam

While many databases are dedicated to organizing protein families and protein domains, Pfam is our preferred database for predicting the function of newly-discovered proteins. Pfam is unique in that it is a manually curated database of protein families derived from protein multiple sequence alignments and profile hidden Markow models. Pfam is a key database for understanding protein function and structure. It is used in many methods, including phylogenetic analysis, secondary structure prediction, and sequence annotation. We're using Pfam Release 7.8.

Sequence Analysis in a Nutshell
Sequence Analysis in a Nutshell: A Guide to Common Tools and Databases
ISBN: 059600494X
EAN: 2147483647
Year: 2005
Pages: 312

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