| Operation/Tool | Windows | Macintosh |
| Arrow tool (select in Toolbox) | V | V |
| Arrow tool (temporary access) | Ctrl | |
| Brush tool (select in Toolbox) | B | B |
| Constrain (ovals to circles, rectangles to squares, lines and rotation to 45-degree angles) | Shift-drag | Shift-drag |
| Convert corner point to curve point (subselection tool) | Alt-drag | Option-drag |
| Create new corner point (arrow tool) | Alt-drag a line | Option-drag a line |
| Drag a copy of selected element on Stage | Alt-drag | Option-drag |
| Drag a copy of selected keyframe unit in Timeline | Alt-drag | Option-drag |
| Dropper tool (select in Toolbox) | I | I |
| End open path (pen tool) | Ctrl-click | -click |
| Eraser tool (select in Toolbox) | E | E |
| Fill Transform tool (select in Toolbox) | F | F |
| Free Transform tool (select in Toolbox) | Q | Q |
| Hand tool (select in Toolbox) | H | H |
| Hand tool (temporary access) | Spacebar | Spacebar |
| Show/Hide all but one layer | Alt-click active layer's eye column | Option-click active layer's eye column |
| Ink bottle tool (select in Toolbox) | S | S |
| Lasso tool (select in Toolbox) | L | L |
| Line tool (select in Toolbox) | N | N |
| Lock/unlock all but one layer | Alt-click active layer's padlock column | Option-click active layer's padlock column |
| Magnifier tool (select in Toolbox) | M, Z | M, Z |
| Magnifier zoom-in tool (temporary access) | Ctrl-Spacebar | -Spacebar |
| Magnifier zoom-out tool (temporary access) | Ctrl-Shift-Spacebar | -Shift-Spacebar |
| Move keyframe unit in Timeline | Click-and-drag | Click-and-drag |
| Nudge selected element down 10pixels | Shift-Down arrow | Shift-Down arrow |
| Nudge selected element to the left 1 pixel | Left arrow | Left arrow |
| Nudge selected element to the left 10 pixels | Shift-Left arrow | Shift-Left arrow |
| Nudge selected element to the right 1 pixel | Right arrow | Right arrow |
| Nudge selected element to the right 10 pixels | Shift-Right arrow | Shift-Right arrow |
| Nudge selected element up 1 pixel | Up arrow | Up arrow |
| Nudge selected element up 10 pixels | Shift-Up arrow | Shift-Up arrow |
| Nudge selected element down 1 pixel | Down arrow | Down arrow |
| Oval tool (select in Toolbox) | O | O |
| Paint bucket tool (select in Toolbox) | K | K |
| Pen tool (select in Toolbox) | P | P |
| Pencil tool (select in Toolbox) | Y | Y |
| Rectangle tool (select in Toolbox) | R | R |
| Select multiple layers | Shift-click | Shift-click |
| Select noncontiguous layers | Ctrl-click | -click |
| Set fill and stroke color simultaneously | Shift-click with the dropper tool | Shift-click with the dropper tool |
| Show outlines for all but one layer | Alt-click that layer's outline column | Option-click that layer's outline column |
| Subselection tool (select in Toolbox) | A | A |
| Switch magnifier tool temporarily from zoom-in to zoom-out and vice versa | Alt | Option |
| Text tool (select in Toolbox) | T | T |