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Hack 9. The Neuron
There's a veritable electrical storm going on inside your head: 100 billion brain cells firing electrical signals at one another are responsible for your every thought and action. A neuron, a.k.a. nerve cell or brain cell, is a specialized cell that sends an electrical impulse out along fibers connecting it, in turn, to other neurons. These guys are the wires of your very own personal circuitry. What follows is a simplistic description of the general features of nerve cells, whether they are found sending signals from your senses to your brain, from your brain to your muscles, or to and from other nerve cells. It's this last class, the kind that people most likely mean when they say "neurons," that we are most interested in here. (All nerve cells, however, share a common basic design.)
The neuron is made up of a cell body with long offshootsthese can be very long (the whole length of the neck, for some neurons in the giraffe, for example) or very short (i.e., reaching only to the neighboring cell, scant millimeters away). Signals pass only one way along a neuron. The offshoots receiving incoming transmissions are called dendrites. The outgoing end, which is typically longer, is called the axon. In most cases there's only one, long, axon, which branches at the tip as it connects to other neuronsup to 10,000 of them. The junction where the axon of one cell meets the dendrites of another is called the synapse. Chemicals, called neurotransmitters, are used to get the signal across the synaptic gap. Each neuron will release only one kind of neurotransmitter, although it may have receptors for many different kinds. The arrival of the electric signal at the end of the axon triggers the release of stores of the neurotransmitter that move across the gap (it's very small, after all) and bind to receptor sites on the other side, places on the neuron that are tuned to join with this specific type of chemical. Whereas the signal between neurons uses neurotransmitters, internally it's electrical. The electrical signal is sent along the neuron in the form of an action potential.2 This is what we mean when we say impulses, signals, spikes, or refer, in brain imaging speak, to the firing or lighting up of brain areas (because this is what activity looks like on the pictures that are made). Action potentials are the fundamental unit of information in the brain, the universal currency of the neural market. The two most important computational features are as follows:
Together these two features mean that the real language of the brain is not just a matter of spikes (signals sent by neurons), but spikes in time. Whether or not a new spike, or impulse, is generated by the postsynaptic neuron (the one on the receiving side of the synapse) is affected by the following interwoven factors:
All of this short-term information is affected by any previous history of interaction between these two neuronstimes one has caused the other to fire and when they have both fired at the same time for independent reasonsand slightly adjusts the probability of interaction happening again.3
After the neurotransmitter has carried (or not carried, as the case may be) the signal across the synaptic gap, it's then broken down by specialized enzymes and reabsorbed to be released again when the next signal comes along. Many drugs work by affecting the rate and quantity of particular neurotransmitters released and the speed at which they are broken down and reabsorbed. Hacks such as [Hack #11] and [Hack #26] show some of the other consequences for psychology of using neurons to do the work. Two good introductions to how neurons combine on a large scale can be found at http://www.foresight.gov.uk/cognitive.html. This is a British government Department of Trade and Industry project that aimed to get neuroscientists and computer scientists to collaborate in producing reviews of recent advances in their fields and summarize the implications for the development of artificial cognitive systems. 1.10.1. End Notes
1.10.2. See Also
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