5.

Appendix D. Normal Laboratory Values

Manual of Rheumatology and Outpatient Orthopedic Disorders

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Appendix D. Normal Laboratory Values

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Stephen A. Paget and Allan Gibofsky

Immunologic
Hematologic
Biochemistry
Endocrine
Quantitative urinary excretion

Table D-1. Normal laboratory values
Tests	Normal values
Immunologic
Rheumatoid factor
Latex fixation	<1.160 titer
Rate nephelometric	<30 IU/mL
Serum complement
Total hemolytic complement (CH 50)	150 “250 Us/mL
Complement components (immunoassays)
C1q	11 “22 mg/dL
C2	1.6 “3.6 mg/dL
C3	64 “210 md/dL
C4	11.5 “50.0 mg/dL
C5	7.1 “20.4 mg/dL
C1 esterase inhibitor	14 “30 mg/dL
Factor B	14.8 “31.0 mg/dL
Antinuclear antibody (ANA)	Negative
Anti-DNA antibody ( Crithidia immunofluorescence)	Negative
Anti-streptolysin O (ASO)	0 “125 Todd units
Serum immunoglobulins (immunoassay)
IgG	723 “1685 mg/dL
IgA	69 “382 mg/dL
IgM	63 “277 mg/dL

Hematologic
Blood counts	Males	Females
CBC (includes five-part differential)	3.5 “10.7	3.5 “10.7
RBC — 10 12 /L	4.2 “5.6	4.0 “5.2
HGB (g/dL)	13 “17	11.5 “16.0
HCT (%)	38 “52	34 “46
MCV (fl)	82 “98	82 “98
PLT — 10 9 /L	160 to 400
Differential	%	Absolute
Neutrophils	40.0 “74.0	1.90 “8.00
Lymphocytes	19.0 “48.0	0.90 “5.20
Monocytes	3.4 “9.0	0.16 “1.00
Eosinophils	0.0 “7.0	0.00 “0.80
Basophils	0.0 “1.5	0.00 “0.20
Larger unstained cells	0.0 “4.0
Stained smears ”bands		0 “12 mm/h males <10%
Sedimentation rate (Westergren)		0 “27 mm/h females
Activated partial thromboplastin time (aPTT)		Upper limit 38.0 sec
Prothrombin time (PT) (dependent on reagent lot No.)		Upper limit 13.0 sec
Fibrinogen		200 “400 mg/dL

Biochemistry
Acid phosphatase (spectrophotometry)	0 “5.5 µ/L
Albumin (modified Doumas)	3.5 “5.0 g/dL
Aldolase (ultraviolet, kinetic)	0 “7.4 µ/L
Alkaline phosphatase (Bowers & McComb)	30 “110 µ/L
Amylase (enzymatic /kinetic)	25 “125 µ/L
Bicarbonate (enzymatic oxidation)	23 “35 mEq/L
Bilirubin, total (azobilirubin)	0 “1.0 mg/dL
Calcium ( o -cresophthalein complex 1)	8.5 “10.5 mg/dL
Chloride (ion-selective electrode)	97 “107 mEq/L
Cholesterol (enzymatic)	150 “240 mg/dL
Creatine kinase (enzymatic/kinetic)	40 “175 females  40 “225 µ/L males
Creatinine (modified Jaffe)	0.4 “1.2 mg/dL
GGTP (modified Rosalki & Tarlow)	0 “70 µ/L
Glucose (hexokinase)	70 “105 mg/dL
Iron (ferrozine)	20 “170 µg/dL  females  20 “200 µg/dL  males
Iron-binding capacity (ferrozine)	250 “450 µg/dL
LDH (modified Amador)	80 “200 µ/L
5'-NT ( enzyme kinetic)	4 “11.5 µ/L
Phosphorus, inorganic (modified Fiske & Subbarow)	2.5 “5.0 mg/dL
Potassium (ion-selective electrode)	3.5 “5.0 mEq/L
Protein, total (Biuret)	6.0 “8.0 g/dL
Salicylate (colorimetric You & Roe) therapeutic level	6 “20 mg/dL
SGOT (AST) (modified Scandinavian)	10 “45 µ/L
SGPT (ALT) (modified Scandinavian)	0 “40 µ/L
Sodium (ion-selective electrode)	135 “145 mEq/L
Triglyceride (enzymatic/colorimetric)	72 “174 mg/dL
Urea nitrogen (modified Talke & Schubert)	5 “25 mg/dL
Uric acid (uricase Trivedi)	2.0 “9.0 mg/dL

Endocrine
T 4 (immunoassay)	4.9 “10.7 µg/dL
T 3 uptake (immunoassay)	28% “36%
T 3 RIA (immunoassay)
0 to 14 y	125 “250 ng/dL
14 to 23 y	100 “220 ng/dL
> 24y	80 “180 ng/dL
Intact PTH (immunochemiluminescent assay)	1.0 “5.0 pmol/L
N-terminal PTH (immunochemiluminescent assay)	0 “6.1 pmol/L
C-terminal PTH (radioimmunoassay)	0 “50 mEq/mL

Quantitative urinary excretion
Calcium	50 “400 mg/24 h
Hydroxyproline, total	15 “45 mg/24 h
Magnesium	75 “150 mg/24 h
Sodium	43 “217 mg/24 h
Potassium	26 “123 mEq/24 h
Phosphorus (inorganic)	340 “1,100 mg/24 h
Amylase (enzymatic/kinetic)	1 “17 U/h
Protein	10 “100 mg/24 h
Creatinine	800 “1,900 mg/24 h
Creatinine clearance	70 “180 mL/min
Uric acid (diet-dependent)	250 “750 mg/24 h

Books@Ovid
Copyright 2000 by Lippincott Williams & Wilkins
Stephen A. Paget, M.D., Allan Gibofsky, M.D., J.D. and John F. Beary, III, M.D.
Manual of Rheumatology and Outpatient Orthopedic Disorders

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