Exchange Server 5.5 cannot be upgraded in-place; you must first upgrade to Exchange 2000 Server and then to Exchange Server 2003, or install Exchange Server 2003 on a different server and move the Exchange Server 5.5 resources to the new server.
Exchange 2000 Server can be upgraded directly to Exchange Server 2003 if the Windows 2000 Server level is SP3 or later.
If you upgrade Exchange 2000 Server to Exchange Server 2003, you must run ForestPrep and DomainPrep again with Exchange Server 2003. The same permissions requirements apply as when installing Exchange Server 2003 in a new organization.
The Migration Wizard can only migrate an Exchange Server organization to another organization. It cannot be used to migrate accounts and mailboxes within an organization.
X.400 connectors can connect other Exchange Server organizations, other Exchange Server routing groups in the same organization, or non–Exchange Server X.400-compliant messaging systems.
The Migration Wizard can migrate previous versions of Exchange Server in other organizations to an Exchange Server 2003 organization, and it can also migrate popular third-party messaging systems, such as Lotus Notes and Novell GroupWise.
Exchange Server 2003 can be configured to synchronize directories with Lotus Notes and Novell GroupWise with connectors that can be installed from the Exchange Server 2003 installation CD.