Once you have a motion path , you can use the Pen tool to add keyframes.
Select a layer with a motion path.
Choose the Pen Tool from the Tools Palette.
Click on the path to add keyframes.
Chose the Selection Tool from the Tools Palette or hold down the Cmd Key (Ctrl) to change the Pen Tool to the Selection Tool, and move these new keyframes to new positions .
When you add keyframes to a motion path by using the Pen Tool you may want to rove the resulting keyframes in time to maintain constant velocity.